Oxidative Stress Induces an Interactive Decline in Wnt and Nrf2 Signaling in Degenerating Retinal Pigment Epithelium.

Ebrahimi, Katayoon B; Cano, Marisol; Rhee, John; Datta, Sayantan; Wang, Lei; Handa, James T

Ebrahimi, Katayoon B; Cano, Marisol; Rhee, John; Datta, Sayantan; Wang, Lei; Handa, James T.

Afiliação

Ebrahimi KB; Wilmer Eye Institute , Johns Hopkins School of Medicine, Baltimore, Maryland.
Cano M; Wilmer Eye Institute , Johns Hopkins School of Medicine, Baltimore, Maryland.
Rhee J; Wilmer Eye Institute , Johns Hopkins School of Medicine, Baltimore, Maryland.
Datta S; Wilmer Eye Institute , Johns Hopkins School of Medicine, Baltimore, Maryland.
Wang L; Wilmer Eye Institute , Johns Hopkins School of Medicine, Baltimore, Maryland.
Handa JT; Wilmer Eye Institute , Johns Hopkins School of Medicine, Baltimore, Maryland.

Antioxid Redox Signal ; 29(4): 389-407, 2018 08 01.

Article em En | MEDLINE | ID: mdl-29186981

Assuntos

Fator 2 Relacionado a NF-E2/metabolismo; Estresse Oxidativo; Epitélio Pigmentado da Retina/metabolismo; Via de Sinalização Wnt; Animais; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout

Palavras-chave

Nrf2; Wnt; age-related macular degeneration; aging; high-fat diet; oxidative stress; smoking

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Oxidativo / Fator 2 Relacionado a NF-E2 / Epitélio Pigmentado da Retina / Via de Sinalização Wnt Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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