Myelodysplastic syndromes without peripheral monocytosis but with evidence of marrow monocytosis share clinical and molecular characteristics with CMML.

Schuler, E; Frank, F; Hildebrandt, B; Betz, B; Strupp, C; Rudelius, M; Aul, C; Schroeder, T; Gattermann, N; Haas, R; Germing, U

Schuler, E; Frank, F; Hildebrandt, B; Betz, B; Strupp, C; Rudelius, M; Aul, C; Schroeder, T; Gattermann, N; Haas, R; Germing, U.

Afiliação

Schuler E; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany. Electronic address: Esther.Schuler@med.uni-duesseldorf.de.
Frank F; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany.
Hildebrandt B; Institute of Human Genetics and Anthropology, Heinrich Heine-University, Duesseldorf, Germany.
Betz B; Institute of Human Genetics and Anthropology, Heinrich Heine-University, Duesseldorf, Germany.
Strupp C; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany.
Rudelius M; Institute of Pathology, Heinrich Heine-University, Duesseldorf, Germany.
Aul C; Department of Hematology and Oncology, Johannes Hospital Duisburg, Germany.
Schroeder T; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany.
Gattermann N; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany.
Haas R; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany.
Germing U; Department of Hematology, Oncology and Clinical Immunology, University Hospital Duesseldorf, Heinrich Heine-University, Duesseldorf, Germany.

Leuk Res ; 65: 1-4, 2018 02.

Article em En | MEDLINE | ID: mdl-29216536

Assuntos

Medula Óssea/patologia; Leucemia Mielomonocítica Crônica/genética; Leucemia Mielomonocítica Crônica/patologia; Monócitos/patologia; Síndromes Mielodisplásicas/genética; Síndromes Mielodisplásicas/patologia; Adulto; Idoso; Idoso de 80 Anos ou mais; Biomarcadores Tumorais/genética; Medula Óssea/enzimologia; Proteínas de Transporte/genética; Proliferação de Células; Subunidade alfa 2 de Fator de Ligação ao Core/genética; Proteínas de Ligação a DNA/genética; Dioxigenases; Esterases/metabolismo; Feminino; Genes ras; Testes Genéticos; Humanos; Masculino; Pessoa de Meia-Idade; Monócitos/enzimologia; Mutação; Taxa de Mutação; Proteínas Nucleares/genética; Prognóstico; Proteínas Proto-Oncogênicas/genética; Proteínas Repressoras/genética; Fatores de Processamento de Serina-Arginina/genética

Palavras-chave

CMML; MDS; MDS/MPN-overlap; Monocytosis; WHO classification

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medula Óssea / Síndromes Mielodisplásicas / Monócitos / Leucemia Mielomonocítica Crônica Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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