Epidemiologic surveillance of multidrug-resistant bacteria in a teaching hospital: A 3-year experience.
Am J Infect Control
; 46(4): 387-392, 2018 Apr.
Article
em En
| MEDLINE
| ID: mdl-29217187
ABSTRACT
BACKGROUND:
The objective of this prospective study was to verify the effectiveness of a multidisciplinary surveillance program that was implemented in a teaching hospital in southern Brazil, to prevent and control the spread of multidrug-resistant organisms.METHODS:
The program implemented involved establishment of prevention guidelines, hand-hygiene promotion, isolation of patients colonized or infected by such organisms, enforced contact precautions, and terminal cleaning and disinfection of isolation rooms. A microbiology service, previously provided by an external laboratory, was established in the hospital. Detection of bacteria-resistant genes and molecular typing were performed also.RESULTS:
Statistically significant differences were observed between the pre- and post-intervention periods (P = .00198). Control measures were effective in blocking the dissemination of a previously endemic clone of Acinetobacter baumannii. Changes were observed in the dissemination pattern, from a monoclonal to a polyclonal mode. The incidence of vancomycin-resistant Enterococcus during the surveillance period was low. Only 2 isolates of BLAKPC-positive Klebsiella pneumoniae (distinct profiles), and 5 isolates of BLASPM-positive Pseudomonas aeruginosa (a single cluster), were detected.CONCLUSIONS:
These results indicate that the surveillance program implemented was effective in preventing the spread of multidrug-resistant organisms in the hospital.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Bactérias
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Farmacorresistência Bacteriana Múltipla
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Monitoramento Epidemiológico
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Antibacterianos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article