Hyper Parathyroidisim Jaw Tumor Syndrome: A Rare Condition of Incongruous Features.
Ethiop J Health Sci
; 27(3): 309-313, 2017 May.
Article
em En
| MEDLINE
| ID: mdl-29217931
ABSTRACT
BACKGROUND:
Hyperparathyroidism-Jaw Tumor (HPT-JT) syndrome is a rare genetic disorder bearing both a germline and a somatic CDC73 mutation (formerly known as HRPT2), which has been mapped to chromosome 1q25-q31. The association of jaw ossifying fibroma with primary hyperparathyroidisim (PHPT) is typical of HPT-JT. It may also include cystic and neoplastic renal abnormalities and uterine tumors. CASE DETAILS Here, we report a case of HPT-JT with an initial presentation of declination in reproductive fitness. Extensive literature search and thorough investigation helped us parturitate the underlying syndrome, thereby predictively improving the prognosis.CONCLUSION:
The features of HPT-JT are clinically difficult to ascertain because the parathyroid disease, ossifying fibroma in the jaw and other abnormalities, often occurs asynchronously and may be diagnosed and treated separately.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Maxilomandibulares
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Adenoma
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Saúde Reprodutiva
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Fibroma
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Hiperparatireoidismo
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Arcada Osseodentária
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article