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Stressing Out PanIN: NRF2 Pushes over the Edge.
Torrente, Laura; DeNicola, Gina M.
Afiliação
  • Torrente L; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
  • DeNicola GM; Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. Electronic address: gina.denicola@moffitt.org.
Cancer Cell ; 32(6): 723-725, 2017 12 11.
Article em En | MEDLINE | ID: mdl-29232549
ABSTRACT
The mechanisms by which chronic stress promote the development of pancreatic ductal adenocarcinoma (PDAC) are poorly defined. In this issue of Cancer Cell, Todoric et al. discover a role for impaired autophagy in the development of PDAC through p62-mediated activation of NRF2.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma in Situ / Carcinoma Ductal Pancreático Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma in Situ / Carcinoma Ductal Pancreático Idioma: En Ano de publicação: 2017 Tipo de documento: Article