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A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim.
Niederalt, Christoph; Kuepfer, Lars; Solodenko, Juri; Eissing, Thomas; Siegmund, Hans-Ulrich; Block, Michael; Willmann, Stefan; Lippert, Jörg.
Afiliação
  • Niederalt C; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 51368, Leverkusen, Germany. christoph.niederalt@bayer.com.
  • Kuepfer L; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 51368, Leverkusen, Germany.
  • Solodenko J; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 51368, Leverkusen, Germany.
  • Eissing T; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 51368, Leverkusen, Germany.
  • Siegmund HU; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 51368, Leverkusen, Germany.
  • Block M; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 51368, Leverkusen, Germany.
  • Willmann S; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 42113, Wuppertal, Germany.
  • Lippert J; Clinical Pharmacometrics, Bayer AG Pharmaceuticals, 42113, Wuppertal, Germany.
J Pharmacokinet Pharmacodyn ; 45(2): 235-257, 2018 04.
Article em En | MEDLINE | ID: mdl-29234936
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Distribuição Tecidual / Proteínas Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Distribuição Tecidual / Proteínas Idioma: En Ano de publicação: 2018 Tipo de documento: Article