Hydrophosphonodifluoromethylation of Alkenes via Thiyl-Radical/Photoredox Catalysis.

ABSTRACT

Visible-light-induced catalytic hydrophosphonodifluoromethylation of mono- and disubstituted alkenes using bromodifluoromethanephosphonate with a Hantzsch ester as the terminal reductant is reported. The combination of thiyl-radical catalysis with photoredox catalysis is important for achieving good chemoselectivity and high yields.