Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway.

Fan, Fan; Wang, Rui; Boulbes, Delphine R; Zhang, Huiyuan; Watowich, Stephanie S; Xia, Ling; Ye, Xiangcang; Bhattacharya, Rajat; Ellis, Lee M

Fan, Fan; Wang, Rui; Boulbes, Delphine R; Zhang, Huiyuan; Watowich, Stephanie S; Xia, Ling; Ye, Xiangcang; Bhattacharya, Rajat; Ellis, Lee M.

Afiliação

Fan F; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Wang R; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Boulbes DR; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Zhang H; Department of Immunology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Watowich SS; Department of Immunology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Xia L; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Ye X; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Bhattacharya R; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.
Ellis LM; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Holcombe Boulevard, Houston, Texas, United States of America.

PLoS One ; 13(1): e0190070, 2018.

Article em En | MEDLINE | ID: mdl-29293549

Assuntos

Neoplasias Colorretais/patologia; Proteínas Hedgehog/metabolismo; Macrófagos/metabolismo; Células-Tronco Neoplásicas/patologia; Animais; Neoplasias Colorretais/metabolismo; Meios de Cultivo Condicionados; Humanos; Camundongos; Células-Tronco Neoplásicas/metabolismo; Fenótipo; Reação em Cadeia da Polimerase Via Transcriptase Reversa

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Colorretais / Proteínas Hedgehog / Macrófagos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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