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Liver nitrosation and inflammation in septic rats were suppressed by propofol via downregulating TLR4/NF-κB-mediated iNOS and IL-6 gene expressions.
Wu, Gong-Jhe; Lin, Yung-Wei; Chuang, Chi-Yuan; Tsai, Hsiao-Chien; Chen, Ruei-Ming.
Afiliação
  • Wu GJ; Department of Anesthesiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Lin YW; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Chuang CY; Comprehensive Cancer Center, Taipei Medical University, Taipei, Taiwan.
  • Tsai HC; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Chen RM; Comprehensive Cancer Center, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: rmchen@tmu.edu.tw.
Life Sci ; 195: 25-32, 2018 Feb 15.
Article em En | MEDLINE | ID: mdl-29307523
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nitrosação / Propofol / NF-kappa B / Interleucina-6 / Sepse / Óxido Nítrico Sintase Tipo II / Receptor 4 Toll-Like / Hepatite / Hipnóticos e Sedativos / Fígado Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nitrosação / Propofol / NF-kappa B / Interleucina-6 / Sepse / Óxido Nítrico Sintase Tipo II / Receptor 4 Toll-Like / Hepatite / Hipnóticos e Sedativos / Fígado Idioma: En Ano de publicação: 2018 Tipo de documento: Article