Five percent of healthy newborns have an <i>ETV6-RUNX1</i> fusion as revealed by DNA-based GIPFEL screening.

Schäfer, Daniel; Olsen, Marianne; Lähnemann, David; Stanulla, Martin; Slany, Robert; Schmiegelow, Kjeld; Borkhardt, Arndt; Fischer, Ute

Five percent of healthy newborns have an ETV6-RUNX1 fusion as revealed by DNA-based GIPFEL screening.

Schäfer, Daniel; Olsen, Marianne; Lähnemann, David; Stanulla, Martin; Slany, Robert; Schmiegelow, Kjeld; Borkhardt, Arndt; Fischer, Ute.

Afiliação

Schäfer D; Department of Pediatric Oncology, Hematology, and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Olsen M; Department of Pediatrics and Adolescent Medicine, The Juliane Marie Centre, The University Hospital Rigshospitalet, Copenhagen, Denmark.
Lähnemann D; Department of Pediatric Oncology, Hematology, and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Stanulla M; Computational Biology of Infection Research, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Slany R; Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.
Schmiegelow K; Department of Genetics, Friedrich Alexander University, Erlangen-Nuremberg, Germany; and.
Borkhardt A; Department of Pediatrics and Adolescent Medicine, The Juliane Marie Centre, The University Hospital Rigshospitalet, Copenhagen, Denmark.
Fischer U; Institute of Clinical Medicine, Faculty of Medicine, University of Copenhagen, Copenhagen, Denmark.

Blood ; 131(7): 821-826, 2018 02 15.

Article em En | MEDLINE | ID: mdl-29311095

Assuntos

Pontos de Quebra do Cromossomo; Subunidade alfa 2 de Fator de Ligação ao Core/genética; Detecção Precoce de Câncer; Proteínas de Fusão Oncogênica/genética; Reação em Cadeia da Polimerase/métodos; Leucemia-Linfoma Linfoblástico de Células Precursoras B/diagnóstico; Voluntários Saudáveis; Humanos; Recém-Nascido; Leucemia-Linfoma Linfoblástico de Células Precursoras B/genética; Estudos Retrospectivos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia-Linfoma Linfoblástico de Células Precursoras B / Proteínas de Fusão Oncogênica / Reação em Cadeia da Polimerase / Subunidade alfa 2 de Fator de Ligação ao Core / Detecção Precoce de Câncer / Pontos de Quebra do Cromossomo Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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