Extensively drug-resistant ArmA-producing Acinetobacter baumannii in an Italian intensive care unit.
New Microbiol
; 41(2): 159-161, 2018 Apr.
Article
em En
| MEDLINE
| ID: mdl-29313866
ABSTRACT
We describe the spread of 12 carbapenem-resistant Acinetobacter baumannii isolates in hospitalized patients. All strains showed an extensively drug-resistant phenotype and high-level of aminoglycoside resistance, harboring the ArmA gene and blaoxa-23 downstream of ISAba1 (transposon Tn2008 arrangement) where both were located on the chromosome. These strains carry a class 1 integron containing the gene cassette aacA4-catB8-aadA1. Molecular analysis revealed that all isolates belonged to the same sequence type (ST) 2 clone. The spread of ArmA-producing A. baumannii strains limit the treatment options showing the dramatic situation which requires novel therapies to limit high mortality rates.
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MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Infecções por Acinetobacter
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Farmacorresistência Bacteriana Múltipla
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Acinetobacter baumannii
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Antibacterianos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article