Salinomycin induces primary chicken cardiomyocytes death via mitochondria mediated apoptosis.

Gao, Xiuge; Zheng, Yani; Ruan, Xiangchun; Ji, Hui; Peng, Lin; Guo, Dawei; Jiang, Shanxiang

Gao, Xiuge; Zheng, Yani; Ruan, Xiangchun; Ji, Hui; Peng, Lin; Guo, Dawei; Jiang, Shanxiang.

Afiliação

Gao X; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China.
Zheng Y; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China; Qingdao Vland Biotech Group Co., Ltd., Qingdao 266100, PR China.
Ruan X; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China; Laboratory of Veterinary Pharmacology and Toxicology, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, PR China.
Ji H; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China.
Peng L; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China.
Guo D; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China.
Jiang S; Laboratory of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China. Electronic address: nauvy@sina.com.

Chem Biol Interact ; 282: 45-54, 2018 Feb 25.

Article em En | MEDLINE | ID: mdl-29331652

Assuntos

Apoptose/efeitos dos fármacos; Morte Celular/efeitos dos fármacos; Mitocôndrias/efeitos dos fármacos; Miócitos Cardíacos/efeitos dos fármacos; Piranos/farmacologia; Animais; Proteínas Reguladoras de Apoptose/metabolismo; Células Cultivadas; Galinhas; Regulação para Baixo/efeitos dos fármacos; Potencial da Membrana Mitocondrial/efeitos dos fármacos; Mitocôndrias/metabolismo; Miócitos Cardíacos/metabolismo; Transdução de Sinais/efeitos dos fármacos; Regulação para Cima/efeitos dos fármacos

Palavras-chave

Apoptosis; Cardiomyocyte; Cytotoxicity; Mitochondrial pathway; Salinomycin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piranos / Morte Celular / Apoptose / Miócitos Cardíacos / Mitocôndrias Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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