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Metabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) in rats and monkeys.
Reddy, Chintam Nagendra; Alhamza, Hussam; Chourey, Shishir; Ye, Qiuji; Gore, Vivek; Cossette, Chantal; Gravel, Sylvie; Slobodchikova, Irina; Vuckovic, Dajana; Rokach, Joshua; Powell, William S.
Afiliação
  • Reddy CN; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901-6982, USA.
  • Alhamza H; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901-6982, USA.
  • Chourey S; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901-6982, USA.
  • Ye Q; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901-6982, USA.
  • Gore V; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901-6982, USA.
  • Cossette C; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, 1001 Decarie Blvd, Montreal, QC H4A 3J1, Canada.
  • Gravel S; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, 1001 Decarie Blvd, Montreal, QC H4A 3J1, Canada.
  • Slobodchikova I; Department of Chemistry and Biochemistry and PERFORM Centre, Concordia University, 7141 Sherbrooke St. W., Montréal, QC H4B 1R6, Canada.
  • Vuckovic D; Department of Chemistry and Biochemistry and PERFORM Centre, Concordia University, 7141 Sherbrooke St. W., Montréal, QC H4B 1R6, Canada.
  • Rokach J; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901-6982, USA.
  • Powell WS; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, 1001 Decarie Blvd, Montreal, QC H4A 3J1, Canada. Electronic address: william.powell@mcgill.ca.
Eur J Pharm Sci ; 115: 88-99, 2018 Mar 30.
Article em En | MEDLINE | ID: mdl-29339225
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores Quimiotáticos / Ácidos Araquidônicos / Receptores Eicosanoides / Eosinófilos / Indóis Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores Quimiotáticos / Ácidos Araquidônicos / Receptores Eicosanoides / Eosinófilos / Indóis Idioma: En Ano de publicação: 2018 Tipo de documento: Article