Validation of the digital PCR system in tyrosine kinase inhibitor-resistant EGFR mutant non-small-cell lung cancer.

Masago, Katsuhiro; Fujita, Shiro; Hata, Akito; Okuda, Chiyuki; Yoshizumi, Yuko; Kaji, Reiko; Katakami, Nobuyuki; Hirata, Yukio; Yatabe, Yasushi

Masago, Katsuhiro; Fujita, Shiro; Hata, Akito; Okuda, Chiyuki; Yoshizumi, Yuko; Kaji, Reiko; Katakami, Nobuyuki; Hirata, Yukio; Yatabe, Yasushi.

Afiliação

Masago K; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Aichi, Japan.
Fujita S; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.
Hata A; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Aichi, Japan.
Okuda C; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.
Yoshizumi Y; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.
Kaji R; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.
Katakami N; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.
Hirata Y; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.
Yatabe Y; Division of Integrated Oncology, Institute of Biomedical Research and Innovation, Kobe, Japan.

Pathol Int ; 68(3): 167-173, 2018 Mar.

Article em En | MEDLINE | ID: mdl-29341374

Assuntos

Carcinoma Pulmonar de Células não Pequenas/genética; Resistencia a Medicamentos Antineoplásicos; Receptores ErbB/genética; Neoplasias Pulmonares/genética; Reação em Cadeia da Polimerase; Adenocarcinoma/genética; Idoso; Idoso de 80 Anos ou mais; Carcinoma Pulmonar de Células não Pequenas/patologia; Resistencia a Medicamentos Antineoplásicos/genética; Feminino; Humanos; Neoplasias Pulmonares/patologia; Masculino; Pessoa de Meia-Idade; Mutação/genética; Reação em Cadeia da Polimerase/métodos; Inibidores de Proteínas Quinases/farmacologia

Palavras-chave

T790M; digital PCR; epidermal growth factor receptor; next generation sequence; re-biopsy

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reação em Cadeia da Polimerase / Carcinoma Pulmonar de Células não Pequenas / Resistencia a Medicamentos Antineoplásicos / Receptores ErbB / Neoplasias Pulmonares Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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