The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6.

Sacristan-Reviriego, Almudena; Bellingham, James; Prodromou, Chrisostomos; Boehm, Annika N; Aichem, Annette; Kumaran, Neruban; Bainbridge, James; Michaelides, Michel; van der Spuy, Jacqueline.

Afiliação

Sacristan-Reviriego A; UCL Institute of Ophthalmology, London EC1V 9EL, UK.
Bellingham J; UCL Institute of Ophthalmology, London EC1V 9EL, UK.
Prodromou C; Genome Damage and Stability Centre, University of Sussex, Brighton, East Sussex BN1?9RQ, UK.
Boehm AN; Biotechnology Institute Thurgau, University of Konstanz, Kreuzlingen, Switzerland.
Aichem A; Biotechnology Institute Thurgau, University of Konstanz, Kreuzlingen, Switzerland.
Kumaran N; UCL Institute of Ophthalmology, London EC1V 9EL, UK.
Bainbridge J; UCL Institute of Ophthalmology, London EC1V 9EL, UK.
Michaelides M; UCL Institute of Ophthalmology, London EC1V 9EL, UK.
van der Spuy J; UCL Institute of Ophthalmology, London EC1V 9EL, UK.

Hum Mol Genet ; 27(7): 1309, 2018 04 01.

Article em En | MEDLINE | ID: mdl-29351602

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article