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Decay of HIV DNA in the Reservoir and the Impact of Short Treatment Interruption in Kenyan Infants.
Pankau, Mark D; Wamalwa, Dalton; Benki-Nugent, Sarah; Tapia, Kenneth; Ngugi, Evelyn; Langat, Agnes; Otieno, Vincent; Moraa, Helen; Maleche-Obimbo, Elizabeth; Overbaugh, Julie; John-Stewart, Grace C; Lehman, Dara A.
Afiliação
  • Pankau MD; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  • Wamalwa D; Department of Global Health, University of Washington, Seattle, Washington.
  • Benki-Nugent S; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
  • Tapia K; Department of Global Health, University of Washington, Seattle, Washington.
  • Ngugi E; Department of Global Health, University of Washington, Seattle, Washington.
  • Langat A; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
  • Otieno V; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
  • Moraa H; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
  • Maleche-Obimbo E; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
  • Overbaugh J; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.
  • John-Stewart GC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington.
  • Lehman DA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Open Forum Infect Dis ; 5(1): ofx268, 2018 Jan.
Article em En | MEDLINE | ID: mdl-29354661
We compared change in HIV reservoir DNA following continued antiretroviral therapy (ART) vs short treatment interruption (TI) in early ART-treated Kenyan infants. While HIV DNA in the reservoir decayed with continued ART, HIV DNA levels were similar to pre-TI HIV DNA reservoir levels in most children after short TI.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article