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Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP.
Piggott, Luke; Silva, Andreia; Robinson, Timothy; Santiago-Gómez, Angelica; Simões, Bruno M; Becker, Michael; Fichtner, Iduna; Andera, Ladislav; Young, Philippa; Morris, Christine; Barrett-Lee, Peter; Alchami, Fouad; Piva, Marco; Vivanco, Maria dM; Clarke, Robert B; Gee, Julia; Clarkson, Richard.
Afiliação
  • Piggott L; European Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, United Kingdom. PiggottL@cardiff.ac.uk.
  • Silva A; European Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
  • Robinson T; European Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
  • Santiago-Gómez A; Breast Biology Group, Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester, United Kingdom.
  • Simões BM; Breast Biology Group, Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester, United Kingdom.
  • Becker M; Experimental Pharmacology and Oncology Berlin-Buch GmbH, Berlin-Buch, Germany.
  • Fichtner I; Experimental Pharmacology and Oncology Berlin-Buch GmbH, Berlin-Buch, Germany.
  • Andera L; Department of Molecular Therapy, Institute of Biotechnology, Academy of Sciences of the Czech Republic, Vestec, Prague, Czech Republic.
  • Young P; Cardiff and Vale UHB Breast Centre, University Hospital of Llandough, Llandough, United Kingdom.
  • Morris C; Cardiff and Vale UHB Breast Centre, University Hospital of Llandough, Llandough, United Kingdom.
  • Barrett-Lee P; Velindre NHS Trust, Cardiff, United Kingdom.
  • Alchami F; Cardiff and Vale UHB, Histopathology, University Hospital Wales, Heath Park, Cardiff, United Kingdom.
  • Piva M; CIC bioGUNE, Technological Park of Bizkaia, Derio, Spain.
  • Vivanco MD; CIC bioGUNE, Technological Park of Bizkaia, Derio, Spain.
  • Clarke RB; Breast Biology Group, Breast Cancer Now Research Unit, Division of Cancer Sciences, Manchester Cancer Research Centre, University of Manchester, Manchester, United Kingdom.
  • Gee J; School of Pharmacology and Pharmaceutical Sciences, King Edward VII Avenue, Cardiff University, Cardiff, United Kingdom.
  • Clarkson R; European Cancer Stem Cell Research Institute, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Clin Cancer Res ; 24(10): 2452-2463, 2018 05 15.
Article em En | MEDLINE | ID: mdl-29363524
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptores de Estrogênio / Processamento de Proteína Pós-Traducional / Resistencia a Medicamentos Antineoplásicos / Ligante Indutor de Apoptose Relacionado a TNF / Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD Idioma: En Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Receptores de Estrogênio / Processamento de Proteína Pós-Traducional / Resistencia a Medicamentos Antineoplásicos / Ligante Indutor de Apoptose Relacionado a TNF / Proteína Reguladora de Apoptosis Semelhante a CASP8 e FADD Idioma: En Ano de publicação: 2018 Tipo de documento: Article