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A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase.
Alturki, Mansour S; Fuanta, Ngolui Rene; Jarrard, Madison A; Hobrath, Judith V; Goodwin, Douglas C; Rants'o, Thankhoe A; Calderón, Angela I.
Afiliação
  • Alturki MS; Department of Drug Discovery and Development, Harrison School of Pharmacy, 4306 Walker Building, Auburn University, Auburn, AL 36849, USA; Department of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia.
  • Fuanta NR; Department of Chemistry and Biochemistry, College of Sciences and Mathematics, 179 Chemistry Building, Auburn University, Auburn, AL 36849, USA.
  • Jarrard MA; Department of Drug Discovery and Development, Harrison School of Pharmacy, 4306 Walker Building, Auburn University, Auburn, AL 36849, USA.
  • Hobrath JV; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.
  • Goodwin DC; Department of Chemistry and Biochemistry, College of Sciences and Mathematics, 179 Chemistry Building, Auburn University, Auburn, AL 36849, USA.
  • Rants'o TA; Department of Drug Discovery and Development, Harrison School of Pharmacy, 4306 Walker Building, Auburn University, Auburn, AL 36849, USA.
  • Calderón AI; Department of Drug Discovery and Development, Harrison School of Pharmacy, 4306 Walker Building, Auburn University, Auburn, AL 36849, USA. Electronic address: aic0001@auburn.edu.
Bioorg Med Chem Lett ; 28(4): 802-808, 2018 02 15.
Article em En | MEDLINE | ID: mdl-29366649
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Fosfotransferases (Aceptor do Grupo Álcool) / Inibidores Enzimáticos / Benzotiazóis Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Fosfotransferases (Aceptor do Grupo Álcool) / Inibidores Enzimáticos / Benzotiazóis Idioma: En Ano de publicação: 2018 Tipo de documento: Article