Cloning and expansion of antigen-specific T cells using iPS cell technology: development of "off-the-shelf" T cells for the use in allogeneic transfusion settings.

Kawamoto, Hiroshi; Masuda, Kyoko; Nagano, Seiji; Maeda, Takuya

Kawamoto, Hiroshi; Masuda, Kyoko; Nagano, Seiji; Maeda, Takuya.

Afiliação

Kawamoto H; Laboratory of Immunology, Institute for Frontier Life and Medical Science, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. kawamoto@infront.kyoto-u.ac.jp.
Masuda K; Laboratory of Immunology, Institute for Frontier Life and Medical Science, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Nagano S; Laboratory of Immunology, Institute for Frontier Life and Medical Science, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.
Maeda T; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Int J Hematol ; 107(3): 271-277, 2018 Mar.

Article em En | MEDLINE | ID: mdl-29388165

Assuntos

Engenharia Celular/métodos; Imunoterapia Adotiva/métodos; Células-Tronco Pluripotentes Induzidas; Leucemia Mieloide Aguda/terapia; Linfócitos T Citotóxicos; Aloenxertos; Antígenos CD8; Genes Codificadores dos Receptores de Linfócitos T; Antígenos HLA; Humanos; Leucemia Mieloide Aguda/genética; Terapia de Alvo Molecular; Proteínas WT1

Palavras-chave

Adoptive immunotherapy; CD8αß T cells; WT1 antigen; iPS cells

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / Leucemia Mieloide Aguda / Imunoterapia Adotiva / Células-Tronco Pluripotentes Induzidas / Engenharia Celular Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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