Lower Quadriceps Rate of Force Development Is Associated With Worsening Physical Function in Adults With or at Risk for Knee Osteoarthritis: 36-Month Follow-Up Data From the Osteoarthritis Initiative.
Arch Phys Med Rehabil
; 99(7): 1352-1359, 2018 07.
Article
em En
| MEDLINE
| ID: mdl-29408538
ABSTRACT
OBJECTIVE:
To determine the association between quadriceps rate of force development (RFD) and decline in self-reported physical function and objective measures of physical performance.DESIGN:
Longitudinal cohort study.SETTING:
Community-based sample from 4 urban areas.PARTICIPANTS:
Osteoarthritis Initiative participants with or at risk for knee osteoarthritis, who had no history of knee/hip replacement, knee injury, or rheumatoid arthritis (N=2630).INTERVENTIONS:
Not applicable. MAIN OUTCOMEMEASURES:
Quadriceps RFD (N/s) was measured during isometric strength testing. Worsening physical function was defined as the minimal clinically important difference for worsening self-reported Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) physical function subscale score, 20-m walk time, and repeated chair stand time over 36 months.RESULTS:
Compared with the slowest tertile of RFD, the fastest tertile had a lower risk for worsening of WOMAC physical function subscale score at 36-month follow-up, with an odds ratio (OR) of .68 (95% confidence interval [CI], .51-.92) after adjustment for age, sex, body mass index, depression, history of chronic diseases, and knee pain. In women, in comparison with the slowest tertile of RFD, the fastest tertile had a lower risk for worsening of WOMAC physical function subscale score at 36-month follow-up, with an adjusted OR of .57 (95% CI, .38-.86). This decreased risk did not reach statistical significance in men (OR, 0.81; 95% CI, 0.52-1.27). No statistically significant associations were detected between baseline RFD and walk or chair stand times.CONCLUSIONS:
Our results indicate that higher RFD is associated with decreased risk for worsening self-reported physical function but not with decreased risk for worsening of physical performance.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Osteoartrite do Joelho
/
Músculo Quadríceps
/
Desempenho Físico Funcional
/
Articulação do Joelho
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article