Leishmania mexicana can utilize amino acids as major carbon sources in macrophages but not in animal models.

Saunders, Eleanor C; Naderer, Thomas; Chambers, Jenny; Landfear, Scott M; McConville, Malcolm J

Saunders, Eleanor C; Naderer, Thomas; Chambers, Jenny; Landfear, Scott M; McConville, Malcolm J.

Afiliação

Saunders EC; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010, Australia.
Naderer T; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010, Australia.
Chambers J; Department of Biochemistry and Molecular Biology, Monash University, Victoria, 3800, Australia.
Landfear SM; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010, Australia.
McConville MJ; Department of Molecular Microbiology & Immunology, Oregon Health Sciences University, Portland, OR 97239, USA.

Mol Microbiol ; 108(2): 143-158, 2018 04.

Article em En | MEDLINE | ID: mdl-29411460

Assuntos

Aminoácidos/metabolismo; Leishmania mexicana/metabolismo; Leishmaniose Cutânea/parasitologia; Macrófagos/parasitologia; Animais; Carbono/metabolismo; Ciclo do Ácido Cítrico; Modelos Animais de Doenças; Feminino; Glucose/metabolismo; Humanos; Leishmania mexicana/genética; Leishmania mexicana/patogenicidade; Camundongos; Camundongos Endogâmicos BALB C; Mitocôndrias/metabolismo; Virulência

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leishmania mexicana / Leishmaniose Cutânea / Aminoácidos / Macrófagos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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