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Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice.
Chen, Xi; Jiang, Xiling; Doddareddy, Rajitha; Geist, Brian; McIntosh, Thomas; Jusko, William J; Zhou, Honghui; Wang, Weirong.
Afiliação
  • Chen X; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • Jiang X; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • Doddareddy R; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • Geist B; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • McIntosh T; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • Jusko WJ; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • Zhou H; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
  • Wang W; Biologics Development Sciences, Janssen BioTherapeutics (X.C., X.J., R.D., B.G., T.M., W.W.) and Global Clinical Pharmacology (H.Z.), Janssen R&D, Spring House, Pennsylvania; and Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, State University of New York a
J Pharmacol Exp Ther ; 365(1): 140-155, 2018 04.
Article em En | MEDLINE | ID: mdl-29420255
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Interleucina-23 / Pesquisa Translacional Biomédica / Modelos Biológicos / Anticorpos Monoclonais Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Interleucina-23 / Pesquisa Translacional Biomédica / Modelos Biológicos / Anticorpos Monoclonais Idioma: En Ano de publicação: 2018 Tipo de documento: Article