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The protein kinase PERK/EIF2AK3 regulates proinsulin processing not via protein synthesis but by controlling endoplasmic reticulum chaperones.
Sowers, Carrie R; Wang, Rong; Bourne, Rebecca A; McGrath, Barbara C; Hu, Jingjie; Bevilacqua, Sarah C; Paton, James C; Paton, Adrienne W; Collardeau-Frachon, Sophie; Nicolino, Marc; Cavener, Douglas R.
Afiliação
  • Sowers CR; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802.
  • Wang R; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802.
  • Bourne RA; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802.
  • McGrath BC; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802.
  • Hu J; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802.
  • Bevilacqua SC; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802.
  • Paton JC; the Department of Molecular and Cellular Biology, Research Centre for Infectious Diseases, University of Adelaide, Adelaide 5005, Australia.
  • Paton AW; the Department of Molecular and Cellular Biology, Research Centre for Infectious Diseases, University of Adelaide, Adelaide 5005, Australia.
  • Collardeau-Frachon S; the Department of Pathology, Hôpital-Femme-Mère-Enfant, Hospices Civils de Lyon, Université Claude Bernard Lyon I and CarMeN, INSERM Unit U1060, 69677 Bron, France, and.
  • Nicolino M; the Service d'endocrinologie et de diabétologie pédiatriques et maladies héréditaires du métabolisme, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon, F-69677 Bron, France.
  • Cavener DR; From the Department of Biology, Penn State University, University Park, Pennsylvania 16802, drc9@psu.edu.
J Biol Chem ; 293(14): 5134-5149, 2018 04 06.
Article em En | MEDLINE | ID: mdl-29444822
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proinsulina / EIF-2 Quinase Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proinsulina / EIF-2 Quinase Idioma: En Ano de publicação: 2018 Tipo de documento: Article