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Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy.
Dal Maso, Emma; Zhu, Yue; Pham, Vi; Reynolds, Christopher A; Deganutti, Giuseppe; Hick, Caroline A; Yang, Dehua; Christopoulos, Arthur; Hay, Debbie L; Wang, Ming-Wei; Sexton, Patrick M; Furness, Sebastian G B; Wootten, Denise.
Afiliação
  • Dal Maso E; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.
  • Zhu Y; The National Center for Drug Screening and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; University of Chinese Academy of Sciences, 19A Yuquan Road,
  • Pham V; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.
  • Reynolds CA; School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom.
  • Deganutti G; School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, United Kingdom.
  • Hick CA; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.
  • Yang D; The National Center for Drug Screening and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Christopoulos A; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia.
  • Hay DL; The University of Auckland, School of Biological Sciences, 3 Symonds Street, Auckland 1142, New Zealand.
  • Wang MW; The National Center for Drug Screening and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Pharmacy, Fudan University, Shanghai 201203, Chin
  • Sexton PM; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia; School of Pharmacy, Fudan University, Shanghai 201203, China. Electronic address: Patrick.sexton@monash.edu.
  • Furness SGB; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia. Electronic address: Sebastian.furness@monash.edu.
  • Wootten D; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, Victoria, Australia. Electronic address: denise.wootten@monash.edu.
Biochem Pharmacol ; 150: 214-244, 2018 04.
Article em En | MEDLINE | ID: mdl-29454620
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores da Calcitonina / Líquido Extracelular Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores da Calcitonina / Líquido Extracelular Idioma: En Ano de publicação: 2018 Tipo de documento: Article