Enhanced chondrogenesis differentiation of human induced pluripotent stem cells by MicroRNA-140 and transforming growth factor beta 3 (TGFß3).

Mahboudi, Hossein; Soleimani, Masoud; Enderami, Seyed Ehsan; Kehtari, Mousa; Ardeshirylajimi, Abdolreza; Eftekhary, Mohamad; Kazemi, Bahram

Mahboudi, Hossein; Soleimani, Masoud; Enderami, Seyed Ehsan; Kehtari, Mousa; Ardeshirylajimi, Abdolreza; Eftekhary, Mohamad; Kazemi, Bahram.

Afiliação

Mahboudi H; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Soleimani M; Hematology Department, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Enderami SE; Department of Stem Cell Biology, Stem Cell Technology Research Center, Tehran, Iran.
Kehtari M; Department of Stem Cell Biology, Stem Cell Technology Research Center, Tehran, Iran.
Ardeshirylajimi A; Department of Tissue Engineering and Regenerative Medicine, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Eftekhary M; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Kazemi B; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Cellular and Molecular Biology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: kazemi@sbmu.ac.ir.

Biologicals ; 52: 30-36, 2018 Mar.

Article em En | MEDLINE | ID: mdl-29456027

Assuntos

Diferenciação Celular/efeitos dos fármacos; Condrócitos/metabolismo; Condrogênese/efeitos dos fármacos; Células-Tronco Pluripotentes Induzidas/metabolismo; MicroRNAs/biossíntese; Fator de Crescimento Transformador beta3/farmacologia; Diferenciação Celular/genética; Condrócitos/citologia; Condrogênese/genética; Células HEK293; Humanos; Células-Tronco Pluripotentes Induzidas/citologia; Lentivirus; MicroRNAs/genética; Transdução Genética

Palavras-chave

Chondrocytes; Osteoarthritis; TGFß3; iPSC; microRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Condrócitos / Condrogênese / MicroRNAs / Fator de Crescimento Transformador beta3 / Células-Tronco Pluripotentes Induzidas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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