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Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents.
Vatner, Daniel F; Goedeke, Leigh; Camporez, Joao-Paulo G; Lyu, Kun; Nasiri, Ali R; Zhang, Dongyan; Bhanot, Sanjay; Murray, Susan F; Still, Christopher D; Gerhard, Glenn S; Shulman, Gerald I; Samuel, Varman T.
Afiliação
  • Vatner DF; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA. daniel.vatner@yale.edu.
  • Goedeke L; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.
  • Camporez JG; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.
  • Lyu K; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Nasiri AR; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.
  • Zhang D; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Bhanot S; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA.
  • Murray SF; Ionis Pharmaceuticals, Carlsbad, CA, 92008, USA.
  • Still CD; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA.
  • Gerhard GS; Obesity Institute, Geisinger Health System, Danville, PA, 17822, USA.
  • Shulman GI; Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208020, New Haven, CT, 06520, USA.
  • Samuel VT; Department of Cellular & Molecular Physiology, Yale University School of Medicine, New Haven, CT, 06520, USA.
Diabetologia ; 61(6): 1435-1446, 2018 06.
Article em En | MEDLINE | ID: mdl-29497783
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Oligonucleotídeos Antissenso / Hormônios Peptídicos / Hepatopatia Gordurosa não Alcoólica / Proteínas Semelhantes a Angiopoietina Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Oligonucleotídeos Antissenso / Hormônios Peptídicos / Hepatopatia Gordurosa não Alcoólica / Proteínas Semelhantes a Angiopoietina Idioma: En Ano de publicação: 2018 Tipo de documento: Article