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Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder.
Matthes, Frank; Massari, Serena; Bochicchio, Anna; Schorpp, Kenji; Schilling, Judith; Weber, Stephanie; Offermann, Nina; Desantis, Jenny; Wanker, Erich; Carloni, Paolo; Hadian, Kamyar; Tabarrini, Oriana; Rossetti, Giulia; Krauss, Sybille.
Afiliação
  • Matthes F; German Center for Neurodegenerative Diseases (DZNE) , Sigmund-Freud-Strasse 27 , 53127 Bonn , Germany.
  • Massari S; Department of Pharmaceutical Science , University of Perugia , Via del Liceo 1 , 06123 Perugia , Italy.
  • Bochicchio A; Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9 , Forschungszentrum Jülich , 52425 Jülich , Germany.
  • Schorpp K; Assay Development and Screening Platform, Institute of Molecular Toxicology and Pharmacology , Helmholtz Zentrum München für Gesundheit und Umwelt , Ingolstädter Landstrasse 1 , 85764 Neuherberg , Germany.
  • Schilling J; German Center for Neurodegenerative Diseases (DZNE) , Sigmund-Freud-Strasse 27 , 53127 Bonn , Germany.
  • Weber S; German Center for Neurodegenerative Diseases (DZNE) , Sigmund-Freud-Strasse 27 , 53127 Bonn , Germany.
  • Offermann N; German Center for Neurodegenerative Diseases (DZNE) , Sigmund-Freud-Strasse 27 , 53127 Bonn , Germany.
  • Desantis J; Department of Pharmaceutical Science , University of Perugia , Via del Liceo 1 , 06123 Perugia , Italy.
  • Wanker E; Neuroproteomics , Max Delbrück Center for Molecular Medicine , Robert-Rössle-Strasse 10 , 13092 Berlin , Germany.
  • Carloni P; Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9 , Forschungszentrum Jülich , 52425 Jülich , Germany.
  • Hadian K; JARA-HPC, Jülich Supercomputing Centre , Forschungszentrum Jülich GmbH , 52425 Jülich , Germany.
  • Tabarrini O; Assay Development and Screening Platform, Institute of Molecular Toxicology and Pharmacology , Helmholtz Zentrum München für Gesundheit und Umwelt , Ingolstädter Landstrasse 1 , 85764 Neuherberg , Germany.
  • Rossetti G; Department of Pharmaceutical Science , University of Perugia , Via del Liceo 1 , 06123 Perugia , Italy.
  • Krauss S; Computational Biomedicine, Institute for Advanced Simulation IAS-5 and Institute of Neuroscience and Medicine INM-9 , Forschungszentrum Jülich , 52425 Jülich , Germany.
ACS Chem Neurosci ; 9(6): 1399-1408, 2018 06 20.
Article em En | MEDLINE | ID: mdl-29506378
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Expansão das Repetições de Trinucleotídeos / Proteína Huntingtina / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Huntington / Expansão das Repetições de Trinucleotídeos / Proteína Huntingtina / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2018 Tipo de documento: Article