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A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway.
Sng, Christopher C T; O'Byrne, Sorcha; Prigozhin, Daniil M; Bauer, Matthias R; Harvey, Jennifer C; Ruhle, Michelle; Challis, Ben G; Lear, Sara; Roberts, Lee D; Workman, Sarita; Janowitz, Tobias; Magiera, Lukasz; Doffinger, Rainer; Buckland, Matthew S; Jodrell, Duncan J; Semple, Robert K; Wilson, Timothy J; Modis, Yorgo; Thaventhiran, James E D.
Afiliação
  • Sng CCT; Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • O'Byrne S; Department of Clinical Immunology, Cambridge University Hospitals National Health Service Trust, Addenbrooke's Hospital, Cambridge, United Kingdom.
  • Prigozhin DM; Molecular Immunity Unit, Department of Medicine, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Bauer MR; Division of Structural Studies, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Harvey JC; Department of Immunology, Royal Free London National Health Service Foundation Trust, London, United Kingdom.
  • Ruhle M; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
  • Challis BG; Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom.
  • Lear S; Department of Clinical Immunology, Cambridge University Hospitals National Health Service Trust, Addenbrooke's Hospital, Cambridge, United Kingdom.
  • Roberts LD; Leeds Institute of Cardiovascular and Metabolic Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT) Laboratories, University of Leeds, Leeds, United Kingdom.
  • Workman S; Department of Immunology, Royal Free London National Health Service Foundation Trust, London, United Kingdom.
  • Janowitz T; Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Magiera L; Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Doffinger R; Department of Clinical Immunology, Cambridge University Hospitals National Health Service Trust, Addenbrooke's Hospital, Cambridge, United Kingdom.
  • Buckland MS; Department of Immunology, Royal Free London National Health Service Foundation Trust, London, United Kingdom.
  • Jodrell DJ; Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Semple RK; Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom; University of Edinburgh Centre for Cardiovascular Sciences, Queen's Medical Research Institute, Little France Crescent, Edinburgh, United Kingdom.
  • Wilson TJ; Department of Microbiology, Miami University, Oxford, Ohio.
  • Modis Y; Molecular Immunity Unit, Department of Medicine, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Thaventhiran JED; Cancer Research UK Cambridge Institute, Cambridge, United Kingdom; Department of Clinical Immunology, Cambridge University Hospitals National Health Service Trust, Addenbrooke's Hospital, Cambridge, United Kingdom; Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, U
J Allergy Clin Immunol ; 142(1): 311-314.e6, 2018 07.
Article em En | MEDLINE | ID: mdl-29522842

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator D do Complemento / Via Alternativa do Complemento / Síndromes de Imunodeficiência Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator D do Complemento / Via Alternativa do Complemento / Síndromes de Imunodeficiência Idioma: En Ano de publicação: 2018 Tipo de documento: Article