Glycoengineering of Mammalian Expression Systems on a Cellular Level.

Heffner, Kelley M; Wang, Qiong; Hizal, Deniz Baycin; Can, Özge; Betenbaugh, Michael J

Heffner, Kelley M; Wang, Qiong; Hizal, Deniz Baycin; Can, Özge; Betenbaugh, Michael J.

Afiliação

Heffner KM; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.
Wang Q; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.
Hizal DB; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.
Can Ö; Department of Medical Engineering, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.
Betenbaugh MJ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA. beten@jhu.edu.

Adv Biochem Eng Biotechnol ; 175: 37-69, 2021.

Article em En | MEDLINE | ID: mdl-29532110

Assuntos

Glicoproteínas; Animais; Células CHO; Cricetinae; Cricetulus; Glicoproteínas/genética; Glicoproteínas/metabolismo; Glicosilação; Proteínas Recombinantes/genética

Palavras-chave

CHO; CRISPR/Cas9; Chinese hamster ovary; Fucosylation; Glycoengineering; Glycomics; Glycoproteomics; Mammalian expression systems; N-linked glycosylation; O-linked glycosylation; Sialylation; TALEN; ZFN

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicoproteínas Idioma: En Ano de publicação: 2021 Tipo de documento: Article