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Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.
Wagner, Jessica; Kline, C Leah; Zhou, Lanlan; Campbell, Kerry S; MacFarlane, Alexander W; Olszanski, Anthony J; Cai, Kathy Q; Hensley, Harvey H; Ross, Eric A; Ralff, Marie D; Zloza, Andrew; Chesson, Charles B; Newman, Jenna H; Kaufman, Howard; Bertino, Joseph; Stein, Mark; El-Deiry, Wafik S.
Afiliação
  • Wagner J; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Molecular Therapeutics Program and Department of Hematology/Oncology.
  • Kline CL; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Molecular Therapeutics Program and Department of Hematology/Oncology.
  • Zhou L; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Molecular Therapeutics Program and Department of Hematology/Oncology.
  • Campbell KS; Blood Cell Development and Function Program, Institute for Cancer Research.
  • MacFarlane AW; Blood Cell Development and Function Program, Institute for Cancer Research.
  • Olszanski AJ; Department of Hematology/Oncology and Molecular Therapeutics Program.
  • Cai KQ; Histopathology Facility.
  • Hensley HH; Biological Imaging Facility, and.
  • Ross EA; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
  • Ralff MD; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Molecular Therapeutics Program and Department of Hematology/Oncology.
  • Zloza A; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
  • Chesson CB; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
  • Newman JH; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
  • Kaufman H; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
  • Bertino J; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
  • Stein M; Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, USA.
  • El-Deiry WS; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Molecular Therapeutics Program and Department of Hematology/Oncology.
J Clin Invest ; 128(6): 2325-2338, 2018 06 01.
Article em En | MEDLINE | ID: mdl-29533922
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Neoplasias Colorretais / Transdução de Sinais / Proliferação de Células / Ligante Indutor de Apoptose Relacionado a TNF / Compostos Heterocíclicos de 4 ou mais Anéis Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Neoplasias Colorretais / Transdução de Sinais / Proliferação de Células / Ligante Indutor de Apoptose Relacionado a TNF / Compostos Heterocíclicos de 4 ou mais Anéis Idioma: En Ano de publicação: 2018 Tipo de documento: Article