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Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells.
Mlambo, Tafadzwa; Nitsch, Sandra; Hildenbeutel, Markus; Romito, Marianna; Müller, Maximilian; Bossen, Claudia; Diederichs, Sven; Cornu, Tatjana I; Cathomen, Toni; Mussolino, Claudio.
Afiliação
  • Mlambo T; Institute for Transfusion Medicine and Gene Therapy, Medical Center - University of Freiburg, Freiburg, Germany.
  • Nitsch S; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Freiburg, Germany.
  • Hildenbeutel M; Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany.
  • Romito M; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Müller M; Institute for Transfusion Medicine and Gene Therapy, Medical Center - University of Freiburg, Freiburg, Germany.
  • Bossen C; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Freiburg, Germany.
  • Diederichs S; Faculty of Biology, University of Freiburg, Freiburg, Germany.
  • Cornu TI; Institute for Transfusion Medicine and Gene Therapy, Medical Center - University of Freiburg, Freiburg, Germany.
  • Cathomen T; Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Freiburg, Germany.
  • Mussolino C; Institute for Transfusion Medicine and Gene Therapy, Medical Center - University of Freiburg, Freiburg, Germany.
Nucleic Acids Res ; 46(9): 4456-4468, 2018 05 18.
Article em En | MEDLINE | ID: mdl-29538770
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inativação Gênica Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inativação Gênica Idioma: En Ano de publicação: 2018 Tipo de documento: Article