Accelerated Progression to Type 1 Diabetes in the Presence of HLA-A*24 and -B*18 Is Restricted to Multiple Islet Autoantibody-Positive Individuals With Distinct HLA-DQ and Autoantibody Risk Profiles.

Balke, Else M; Balti, Eric V; Van der Auwera, Bart; Weets, Ilse; Costa, Olivier; Demeester, Simke; Abrams, Pascale; Casteels, Kristina; Coeckelberghs, Marina; Tenoutasse, Sylvie; Keymeulen, Bart; Pipeleers, Daniel G; Gorus, Frans K

Accelerated Progression to Type 1 Diabetes in the Presence of HLA-A*24 and -B*18 Is Restricted to Multiple Islet Autoantibody-Positive Individuals With Distinct HLA-DQ and Autoantibody Risk Profiles.

Balke, Else M; Balti, Eric V; Van der Auwera, Bart; Weets, Ilse; Costa, Olivier; Demeester, Simke; Abrams, Pascale; Casteels, Kristina; Coeckelberghs, Marina; Tenoutasse, Sylvie; Keymeulen, Bart; Pipeleers, Daniel G; Gorus, Frans K.

Afiliação

Balke EM; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium else.balke@vub.be.
Balti EV; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Van der Auwera B; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Weets I; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Costa O; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Demeester S; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Abrams P; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Casteels K; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Coeckelberghs M; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Tenoutasse S; Department of Clinical Chemistry, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Keymeulen B; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.
Pipeleers DG; Department of Endocrinology and Diabetology, GasthuisZusters Antwerpen Campus Sint Augustinus en Sint Vincentius, Antwerp, Belgium.
Gorus FK; Diabetes Research Center, Vrije Universiteit Brussel, Brussels, Belgium.

Diabetes Care ; 41(5): 1076-1083, 2018 05.

Article em En | MEDLINE | ID: mdl-29545461

Assuntos

Autoanticorpos/sangue; Autoimunidade/genética; Diabetes Mellitus Tipo 1/patologia; Antígeno HLA-A24/genética; Antígeno HLA-B18/genética; Antígenos HLA-DQ/genética; Ilhotas Pancreáticas/imunologia; Adolescente; Adulto; Criança; Pré-Escolar; Diabetes Mellitus Tipo 1/sangue; Diabetes Mellitus Tipo 1/genética; Diabetes Mellitus Tipo 1/imunologia; Progressão da Doença; Feminino; Predisposição Genética para Doença; Genótipo; Humanos; Lactente; Recém-Nascido; Anticorpos Anti-Insulina/sangue; Masculino; Sistema de Registros; Fatores de Risco; Adulto Jovem

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoanticorpos / Antígenos HLA-DQ / Autoimunidade / Ilhotas Pancreáticas / Diabetes Mellitus Tipo 1 / Antígeno HLA-A24 / Antígeno HLA-B18 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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