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NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K/Akt/mTOR signalling pathway to improve functional recovery after traumatic brain injury.
Xu, Kebin; Wu, Fangfang; Xu, Ke; Li, Zhengmao; Wei, Xiaojie; Lu, Qi; Jiang, Ting; Wu, Fenzan; Xu, Xinlong; Xiao, Jian; Chen, Daqing; Zhang, Hongyu.
Afiliação
  • Xu K; Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
  • Wu F; Department of Emergency, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.
  • Xu K; Institute of Life Sciences, Wenzhou University, Wenzhou 325035, Zhejiang, China.
  • Li Z; Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
  • Wei X; Department of Neurosurgery, Cixi People's Hospital, Wenzhou Medical University, Ningbo 315300, Zhejiang, China.
  • Lu Q; Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
  • Jiang T; Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
  • Wu F; Science and Education Division, Cixi People's Hospital, Wenzhou Medical University, Ningbo 315300, Zhejiang, China.
  • Xu X; Department of Neurosurgery, Cixi People's Hospital, Wenzhou Medical University, Ningbo 315300, Zhejiang, China.
  • Xiao J; Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China.
  • Chen D; Department of Emergency, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang, China. Electronic address: cdq@wzhealth.com.
  • Zhang H; Key Laboratory of Biotechnology and Pharmaceutical Engineering, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, Zhejiang, China; Experimental Research Centre, Dongyang People's Hospital, Wenzhou Medical University, Jinhua 322100, Zhejiang, China. Electronic address: hy
Chem Biol Interact ; 286: 96-105, 2018 Apr 25.
Article em En | MEDLINE | ID: mdl-29567101
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Sulfetos / Transdução de Sinais / Lesões Encefálicas Traumáticas / Mitocôndrias Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Sulfetos / Transdução de Sinais / Lesões Encefálicas Traumáticas / Mitocôndrias Idioma: En Ano de publicação: 2018 Tipo de documento: Article