Can serum soluble urokinase plasminogen activator receptor be an effective marker in the diagnosis of appendicitis and differentiation of complicated cases?
Ulus Travma Acil Cerrahi Derg
; 24(2): 110-115, 2018 Mar.
Article
em En
| MEDLINE
| ID: mdl-29569681
ABSTRACT
BACKGROUND:
Soluble urokinase plasminogen activator receptor (suPAR) is a new biomarker of inflammation level. The aim of the study was to evaluate whether suPAR levels could be useful to detect acute appendicitis and to differentiate uncomplicated appendicitis (UA) from complicated appendicitis (CA).METHODS:
We prospectively studied 105 patients consisting of 40 UA cases, 40 CA cases, and 25 control patients. Blood samples were collected to measure suPAR level, C-reactive protein level, leukocyte counts, neutrophil counts, and neutrophil percentages preoperatively.RESULTS:
Median values of suPAR level, C-reactive protein level, leukocyte counts, neutrophil counts, and neutrophil percentages in UA and CA were significantly higher than control patients. suPAR levels of the UA and CA groups showed a statistically significant difference (p=0.016).CONCLUSION:
The current study demonstrated that serum suPAR concentrations can be helpful in differentiating CA from UA and in diagnosing acute appendicitis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Apendicite
/
Biomarcadores
/
Receptores de Ativador de Plasminogênio Tipo Uroquinase
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article