Combination of Amphotericin B and Terbinafine against Melanized Fungi Associated with Chromoblastomycosis.
Antimicrob Agents Chemother
; 62(6)2018 06.
Article
em En
| MEDLINE
| ID: mdl-29581111
ABSTRACT
Our in vitro studies showed that a combination of amphotericin B and terbinafine had synergistic effects against the majority of melanized fungi associated with chromoblastomycosis (CBM) and similar infections, including those with Cladophialophora carrionii, Cladophialophora arxii, Exophialadermatitidis, Exophialaspinifera, Fonsecaea monophora, Fonsecaea nubica, Fonsecaea pedrosoi, and Phialophora verrucosa. This drug combination could provide an option for the treatment of severe or unresponsive cases of CBM, particularly in cases due to species of Fonsecaea and Cladophialophora.
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Base de dados:
MEDLINE
Assunto principal:
Anfotericina B
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Cromoblastomicose
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Terbinafina
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Antifúngicos
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article