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Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.
Lacy, Michael; Kontos, Christos; Brandhofer, Markus; Hille, Kathleen; Gröning, Sabine; Sinitski, Dzmitry; Bourilhon, Priscila; Rosenberg, Eric; Krammer, Christine; Thavayogarajah, Tharshika; Pantouris, Georgios; Bakou, Maria; Weber, Christian; Lolis, Elias; Bernhagen, Jürgen; Kapurniotu, Aphrodite.
Afiliação
  • Lacy M; Department of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Feodor-Lynen-Str. 17, D-81377, Munich, Germany.
  • Kontos C; Division of Peptide Biochemistry, Technische Universität München, D-85354, Freising-Weihenstephan, Germany.
  • Brandhofer M; Department of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Feodor-Lynen-Str. 17, D-81377, Munich, Germany.
  • Hille K; Division of Peptide Biochemistry, Technische Universität München, D-85354, Freising-Weihenstephan, Germany.
  • Gröning S; Department of Anaesthesiology, RWTH Aachen University Hospital, D-52074, Aachen, Germany.
  • Sinitski D; Department of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Feodor-Lynen-Str. 17, D-81377, Munich, Germany.
  • Bourilhon P; Department of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Feodor-Lynen-Str. 17, D-81377, Munich, Germany.
  • Rosenberg E; Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, USA.
  • Krammer C; Department of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Feodor-Lynen-Str. 17, D-81377, Munich, Germany.
  • Thavayogarajah T; Department of Vascular Biology, Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Feodor-Lynen-Str. 17, D-81377, Munich, Germany.
  • Pantouris G; Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, USA.
  • Bakou M; Division of Peptide Biochemistry, Technische Universität München, D-85354, Freising-Weihenstephan, Germany.
  • Weber C; Institute for Cardiovascular Prevention, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Pettenkofer Str. 8, D-80336, Munich, Germany.
  • Lolis E; Munich Heart Alliance, D-80802, Munich, Germany.
  • Bernhagen J; Cardiovascular Research Institute Maastricht, Maastricht University, 6229, Maastricht, The Netherlands.
  • Kapurniotu A; Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, USA.
Sci Rep ; 8(1): 5171, 2018 03 26.
Article em En | MEDLINE | ID: mdl-29581527
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ligação Proteica / Relação Estrutura-Atividade / Fatores Inibidores da Migração de Macrófagos / Oxirredutases Intramoleculares / Receptores CXCR4 Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ligação Proteica / Relação Estrutura-Atividade / Fatores Inibidores da Migração de Macrófagos / Oxirredutases Intramoleculares / Receptores CXCR4 Idioma: En Ano de publicação: 2018 Tipo de documento: Article