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The dTAG system for immediate and target-specific protein degradation.
Nabet, Behnam; Roberts, Justin M; Buckley, Dennis L; Paulk, Joshiawa; Dastjerdi, Shiva; Yang, Annan; Leggett, Alan L; Erb, Michael A; Lawlor, Matthew A; Souza, Amanda; Scott, Thomas G; Vittori, Sarah; Perry, Jennifer A; Qi, Jun; Winter, Georg E; Wong, Kwok-Kin; Gray, Nathanael S; Bradner, James E.
Afiliação
  • Nabet B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Roberts JM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Buckley DL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Paulk J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Dastjerdi S; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Yang A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Leggett AL; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Erb MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lawlor MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Souza A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Scott TG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Vittori S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Perry JA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Qi J; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Winter GE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wong KK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Gray NS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bradner JE; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Nat Chem Biol ; 14(5): 431-441, 2018 05.
Article em En | MEDLINE | ID: mdl-29581585

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Proteínas Proto-Oncogênicas p21(ras) / Proteína 1A de Ligação a Tacrolimo / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Nucleares / Proteínas Proto-Oncogênicas p21(ras) / Proteína 1A de Ligação a Tacrolimo / Sistemas CRISPR-Cas Idioma: En Ano de publicação: 2018 Tipo de documento: Article