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Building Bonds: Cancer Stem Cells Depend on Their Progeny to Drive Tumor Progression.
Muthukrishnan, Sree Deepthi; Alvarado, Alvaro G; Kornblum, Harley I.
Afiliação
  • Muthukrishnan SD; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  • Alvarado AG; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  • Kornblum HI; The Intellectual and Developmental Disabilities Research Center, The Semel Institute for Neuroscience and Human Behavior, and The Broad Stem Cell Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; The Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address: hkornblum@mednet.ucla.edu.
Cell Stem Cell ; 22(4): 473-474, 2018 04 05.
Article em En | MEDLINE | ID: mdl-29625062
Little is currently known about how cancer stem-like cells (CSCs) interact with their more restricted progeny. In this issue of Cell Stem Cell, Wang et al. (2018) demonstrate a novel bidirectional signaling axis between CSCs and their progeny that is mediated by brain-derived neurotrophic factor and VGF accelerating glioma progression.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Glioma Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Glioma Idioma: En Ano de publicação: 2018 Tipo de documento: Article