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The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate.
Barros-Álvarez, Ximena; Turley, Stewart; Ranade, Ranae M; Gillespie, J Robert; Duster, Nicole A; Verlinde, Christophe L M J; Fan, Erkang; Buckner, Frederick S; Hol, Wim G J.
Afiliação
  • Barros-Álvarez X; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Turley S; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Ranade RM; Division of Allergy and Infectious Diseases, School of Medicine, University of Washington, Seattle, Washington, USA.
  • Gillespie JR; Division of Allergy and Infectious Diseases, School of Medicine, University of Washington, Seattle, Washington, USA.
  • Duster NA; Division of Allergy and Infectious Diseases, School of Medicine, University of Washington, Seattle, Washington, USA.
  • Verlinde CLMJ; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Fan E; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Buckner FS; Division of Allergy and Infectious Diseases, School of Medicine, University of Washington, Seattle, Washington, USA.
  • Hol WGJ; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
Acta Crystallogr F Struct Biol Commun ; 74(Pt 4): 245-254, 2018 04 01.
Article em En | MEDLINE | ID: mdl-29633973
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Metionina tRNA Ligase / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Metionina tRNA Ligase / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2018 Tipo de documento: Article