Activity of Antimicrobial Peptide Aggregates Decreases with Increased Cell Membrane Embedding Free Energy Cost.

Zou, Rongfeng; Zhu, Xiaomin; Tu, Yaoquan; Wu, Junchen; Landry, Markita P

Zou, Rongfeng; Zhu, Xiaomin; Tu, Yaoquan; Wu, Junchen; Landry, Markita P.

Afiliação

Zou R; Key Laboratory for Advanced Materials & Institute of Fine Chemicals, School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China.
Zhu X; Division of Theoretical Chemistry and Biology, School of Biotechnology , KTH Royal Institute of Technology , SE-10691 Stockholm , Sweden.
Tu Y; Key Laboratory for Advanced Materials & Institute of Fine Chemicals, School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China.
Wu J; Division of Theoretical Chemistry and Biology, School of Biotechnology , KTH Royal Institute of Technology , SE-10691 Stockholm , Sweden.
Landry MP; Key Laboratory for Advanced Materials & Institute of Fine Chemicals, School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China.

Biochemistry ; 57(18): 2606-2610, 2018 05 08.

Article em En | MEDLINE | ID: mdl-29638118

Assuntos

Peptídeos Catiônicos Antimicrobianos/química; Metabolismo Energético/efeitos dos fármacos; Agregados Proteicos/efeitos dos fármacos; Peptídeos Catiônicos Antimicrobianos/metabolismo; Peptídeos Catiônicos Antimicrobianos/farmacologia; Membrana Celular/química; Membrana Celular/efeitos dos fármacos; Bactérias Gram-Negativas/efeitos dos fármacos; Bactérias Gram-Negativas/patogenicidade; Humanos; Simulação de Dinâmica Molecular

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Catiônicos Antimicrobianos / Metabolismo Energético / Agregados Proteicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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