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Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia.
Carvajal, Luis A; Neriah, Daniela Ben; Senecal, Adrien; Benard, Lumie; Thiruthuvanathan, Victor; Yatsenko, Tatyana; Narayanagari, Swathi-Rao; Wheat, Justin C; Todorova, Tihomira I; Mitchell, Kelly; Kenworthy, Charles; Guerlavais, Vincent; Annis, D Allen; Bartholdy, Boris; Will, Britta; Anampa, Jesus D; Mantzaris, Ioannis; Aivado, Manuel; Singer, Robert H; Coleman, Robert A; Verma, Amit; Steidl, Ulrich.
Afiliação
  • Carvajal LA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Neriah DB; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Senecal A; Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Benard L; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Thiruthuvanathan V; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Yatsenko T; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Narayanagari SR; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Wheat JC; Ruth L. and David S. Gottesman Institute for Stem Cell Research and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Todorova TI; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Mitchell K; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Kenworthy C; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Guerlavais V; Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Annis DA; Aileron Therapeutics, Cambridge, MA 02139, USA.
  • Bartholdy B; Aileron Therapeutics, Cambridge, MA 02139, USA.
  • Will B; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Anampa JD; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Mantzaris I; Ruth L. and David S. Gottesman Institute for Stem Cell Research and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Aivado M; Division of Hemato-Oncology, Department of Medicine (Oncology), Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Singer RH; Albert Einstein Cancer Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Coleman RA; Division of Hemato-Oncology, Department of Medicine (Oncology), Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Verma A; Division of Hemato-Oncology, Department of Medicine (Oncology), Albert Einstein College of Medicine, Bronx, NY 10461, USA.
  • Steidl U; Aileron Therapeutics, Cambridge, MA 02139, USA.
Sci Transl Med ; 10(436)2018 04 11.
Article em En | MEDLINE | ID: mdl-29643228
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Leucemia Mieloide Aguda / Proteínas Proto-Oncogênicas / Proteínas Proto-Oncogênicas c-mdm2 Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Leucemia Mieloide Aguda / Proteínas Proto-Oncogênicas / Proteínas Proto-Oncogênicas c-mdm2 Idioma: En Ano de publicação: 2018 Tipo de documento: Article