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Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Chen, Qiuying; Kirk, Kathryne; Shurubor, Yevgeniya I; Zhao, Dazhi; Arreguin, Andrea J; Shahi, Ifrah; Valsecchi, Federica; Primiano, Guido; Calder, Elizabeth L; Carelli, Valerio; Denton, Travis T; Beal, M Flint; Gross, Steven S; Manfredi, Giovanni; D'Aurelio, Marilena.
Afiliação
  • Chen Q; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.
  • Kirk K; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Shurubor YI; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Zhao D; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Arreguin AJ; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Shahi I; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Valsecchi F; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Primiano G; Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.
  • Calder EL; Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute for Cancer Research, New York, NY 10065, USA.
  • Carelli V; IRCCS, Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy; Department of Biomedical and NeuroMotor Sciences (DIBINEM), University of Bologna, Bologna, Italy.
  • Denton TT; Department of Pharmaceutical Sciences, Washington State University, College of Pharmacy, Spokane, WA 99210, USA.
  • Beal MF; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
  • Gross SS; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.
  • Manfredi G; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: gim2004@med.cornell.edu.
  • D'Aurelio M; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: mad2003@med.cornell.edu.
Cell Metab ; 27(5): 1007-1025.e5, 2018 May 01.
Article em En | MEDLINE | ID: mdl-29657030

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Miopatias Mitocondriais / Glutamina / Ácidos Cetoglutáricos / Mitocôndrias Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Miopatias Mitocondriais / Glutamina / Ácidos Cetoglutáricos / Mitocôndrias Idioma: En Ano de publicação: 2018 Tipo de documento: Article