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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.
Kovtun, Yelena; Jones, Gregory E; Adams, Sharlene; Harvey, Lauren; Audette, Charlene A; Wilhelm, Alan; Bai, Chen; Rui, Lingyun; Laleau, Rassol; Liu, Fenghua; Ab, Olga; Setiady, Yulius; Yoder, Nicholas C; Goldmacher, Victor S; Chari, Ravi V J; Pinkas, Jan; Chittenden, Thomas.
Afiliação
  • Kovtun Y; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Jones GE; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Adams S; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Harvey L; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Audette CA; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Wilhelm A; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Bai C; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Rui L; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Laleau R; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Liu F; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Ab O; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Setiady Y; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Yoder NC; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Goldmacher VS; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Chari RVJ; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Pinkas J; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
  • Chittenden T; Science, Technology, and Translation, ImmunoGen, Inc, Waltham MA.
Blood Adv ; 2(8): 848-858, 2018 04 24.
Article em En | MEDLINE | ID: mdl-29661755

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Imunoconjugados / Subunidade alfa de Receptor de Interleucina-3 Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Imunoconjugados / Subunidade alfa de Receptor de Interleucina-3 Idioma: En Ano de publicação: 2018 Tipo de documento: Article