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A TLR/AKT/FoxO3 immune tolerance-like pathway disrupts the repair capacity of oligodendrocyte progenitors.
Srivastava, Taasin; Diba, Parham; Dean, Justin M; Banine, Fatima; Shaver, Daniel; Hagen, Matthew; Gong, Xi; Su, Weiping; Emery, Ben; Marks, Daniel L; Harris, Edward N; Baggenstoss, Bruce; Weigel, Paul H; Sherman, Larry S; Back, Stephen A.
Afiliação
  • Srivastava T; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Diba P; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Dean JM; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Banine F; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.
  • Shaver D; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Hagen M; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Gong X; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Su W; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.
  • Emery B; Department of Neurology, OHSU, Portland, Oregon, USA.
  • Marks DL; Department of Pediatrics, Oregon Health & Science University (OHSU), Portland, Oregon, USA.
  • Harris EN; Department of Biochemistry, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.
  • Baggenstoss B; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
  • Weigel PH; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
  • Sherman LS; Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA.
  • Back SA; Department of Cell, Developmental and Cancer Biology, OHSU, Portland, Oregon, USA.
J Clin Invest ; 128(5): 2025-2041, 2018 05 01.
Article em En | MEDLINE | ID: mdl-29664021

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas Proto-Oncogênicas c-akt / Receptores Toll-Like / Proteína Forkhead Box O3 / Células Precursoras de Oligodendrócitos / Tolerância Imunológica Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Proteínas Proto-Oncogênicas c-akt / Receptores Toll-Like / Proteína Forkhead Box O3 / Células Precursoras de Oligodendrócitos / Tolerância Imunológica Idioma: En Ano de publicação: 2018 Tipo de documento: Article