Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.

Alenazi, Yara; Singh, Kamayani; Davies, Graham; Eaton, James R O; Elders, Philip; Kawamura, Akane; Bhattacharya, Shoumo

Alenazi, Yara; Singh, Kamayani; Davies, Graham; Eaton, James R O; Elders, Philip; Kawamura, Akane; Bhattacharya, Shoumo.

Afiliação

Alenazi Y; RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
Singh K; RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
Davies G; RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
Eaton JRO; RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
Elders P; Department of Chemistry, University of Oxford, Oxford, United Kingdom.
Kawamura A; RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.
Bhattacharya S; RDM Division of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom.

Sci Rep ; 8(1): 6333, 2018 04 20.

Article em En | MEDLINE | ID: mdl-29679010

Assuntos

Receptores CXCR/metabolismo; Receptores de Quimiocinas/metabolismo; Carrapatos/metabolismo; Sequência de Aminoácidos; Animais; Aracnídeos/metabolismo; Quimiocinas/metabolismo; Quimiocinas CC/metabolismo; Quimiocinas CXC/metabolismo; Engenharia Genética; Células HEK293; Humanos; Ligação Proteica; Receptores CXCR/genética; Saccharomyces cerevisiae/metabolismo; Células THP-1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carrapatos / Receptores de Quimiocinas / Receptores CXCR Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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