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Development of an RNA-based kit for easy generation of TCR-engineered lymphocytes to control T-cell assay performance.
Bidmon, Nicole; Kind, Sonja; Welters, Marij J P; Joseph-Pietras, Deborah; Laske, Karoline; Maurer, Dominik; Hadrup, Sine Reker; Schreibelt, Gerty; Rae, Richard; Sahin, Ugur; Gouttefangeas, Cécile; Britten, Cedrik M; van der Burg, Sjoerd H.
Afiliação
  • Bidmon N; Translational Oncology at the University Medical Center of the Johannes-Gutenberg University Mainz (TRON gGmbH), Freiligrathstraße 12, Mainz 55131, Germany; BioNTech AG, An der Goldgrube 12, 55131 Mainz, Germany.
  • Kind S; BioNTech AG, An der Goldgrube 12, 55131 Mainz, Germany.
  • Welters MJP; Department of Medical Oncology, Leiden University Medical Center, Albinusdreef 2, Leiden, ZA 2333, The Netherlands.
  • Joseph-Pietras D; ECMC, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Tremona Road, Southampton SO16 6YD, United Kingdom.
  • Laske K; Department of Immunology, University of Tuebingen, Auf der Morgenstelle 15, Tuebingen 72076, Germany.
  • Maurer D; Immatics biotechnologies GmbH, Paul-Ehrlich-Str. 15, Tuebingen 72076, Germany.
  • Hadrup SR; Laboratory of Hematology, University Hospital Herlev, Ringvej 75, Herlev DK-2730, Denmark.
  • Schreibelt G; Dept. of Tumor Immunology, Radboud university medical center, Radboud Institute for Molecular Life Sciences, P.O. Box 9101, Nijmegen, HB 6500, The Netherlands.
  • Rae R; Translational Oncology at the University Medical Center of the Johannes-Gutenberg University Mainz (TRON gGmbH), Freiligrathstraße 12, Mainz 55131, Germany.
  • Sahin U; Translational Oncology at the University Medical Center of the Johannes-Gutenberg University Mainz (TRON gGmbH), Freiligrathstraße 12, Mainz 55131, Germany; University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, Mainz D-55131, Germany; BioNTech AG, An der Goldgrub
  • Gouttefangeas C; Department of Immunology, University of Tuebingen, Auf der Morgenstelle 15, Tuebingen 72076, Germany.
  • Britten CM; Translational Oncology at the University Medical Center of the Johannes-Gutenberg University Mainz (TRON gGmbH), Freiligrathstraße 12, Mainz 55131, Germany.
  • van der Burg SH; Department of Medical Oncology, Leiden University Medical Center, Albinusdreef 2, Leiden, ZA 2333, The Netherlands. Electronic address: shvdburg@lumc.nl.
J Immunol Methods ; 458: 74-82, 2018 07.
Article em En | MEDLINE | ID: mdl-29684430

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bioensaio / RNA Mensageiro / Linfócitos T / Engenharia Celular / Receptores de Antígenos Quiméricos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bioensaio / RNA Mensageiro / Linfócitos T / Engenharia Celular / Receptores de Antígenos Quiméricos Idioma: En Ano de publicação: 2018 Tipo de documento: Article