ß Cell GLP-1R Signaling Alters &#945; Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice.

Garibay, Darline; Lou, Jon; Lee, Seon A; Zaborska, Karolina E; Weissman, Margot H; Sloma, Erica; Donahue, Leanne; Miller, Andrew D; White, Andrew C; Michael, M Dodson; Sloop, Kyle W; Cummings, Bethany P

ß Cell GLP-1R Signaling Alters α Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice.

Garibay, Darline; Lou, Jon; Lee, Seon A; Zaborska, Karolina E; Weissman, Margot H; Sloma, Erica; Donahue, Leanne; Miller, Andrew D; White, Andrew C; Michael, M Dodson; Sloop, Kyle W; Cummings, Bethany P.

Afiliação

Garibay D; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Lou J; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Lee SA; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Zaborska KE; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Weissman MH; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Sloma E; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Donahue L; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Miller AD; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
White AC; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.
Michael MD; Diabetes and Complications, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
Sloop KW; Diabetes and Complications, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
Cummings BP; Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA. Electronic address: bpc68@cornell.edu.

Cell Rep ; 23(4): 967-973, 2018 04 24.

Article em En | MEDLINE | ID: mdl-29694904

Assuntos

Gastrectomia; Receptor do Peptídeo Semelhante ao Glucagon 1/metabolismo; Células Secretoras de Glucagon/metabolismo; Células Secretoras de Insulina/metabolismo; Comunicação Parácrina; Proglucagon/metabolismo; Transdução de Sinais; Animais; Cirurgia Bariátrica; Receptor do Peptídeo Semelhante ao Glucagon 1/genética; Células Secretoras de Glucagon/patologia; Células Secretoras de Insulina/patologia; Camundongos; Camundongos Knockout; Proglucagon/genética; Pró-Proteína Convertases/genética; Pró-Proteína Convertases/metabolismo

Palavras-chave

GLP-1; prohormone convertase 1/3; vertical sleeve gastrectomy; ß cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Comunicação Parácrina / Células Secretoras de Glucagon / Células Secretoras de Insulina / Proglucagon / Receptor do Peptídeo Semelhante ao Glucagon 1 / Gastrectomia Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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