Synthesis of an Array Comprising 837 Variants of the hYAP WW Protein Domain.

Toepert, Florian; Pires, José R; Landgraf, Christiane; Oschkinat, Hartmut; Schneider-Mergener, Jens

Toepert, Florian; Pires, José R; Landgraf, Christiane; Oschkinat, Hartmut; Schneider-Mergener, Jens.

Afiliação

Toepert F; Institut für Medizinische Immunologie Charité, Humboldt-Universität Berlin Schumannstrasse 20-21, 10098 Berlin (Germany) Fax: (+49) 030-2802-6460.
Pires JR; Forschungsinstitut für Molekulare Pharmakologie Robert-Rössle-Strasse 10, 13125 Berlin (Germany).
Landgraf C; Institut für Medizinische Immunologie Charité, Humboldt-Universität Berlin Schumannstrasse 20-21, 10098 Berlin (Germany) Fax: (+49) 030-2802-6460.
Oschkinat H; Forschungsinstitut für Molekulare Pharmakologie Robert-Rössle-Strasse 10, 13125 Berlin (Germany).
Schneider-Mergener J; Institut für Medizinische Immunologie Charité, Humboldt-Universität Berlin Schumannstrasse 20-21, 10098 Berlin (Germany) Fax: (+49) 030-2802-6460.

Angew Chem Int Ed Engl ; 40(5): 897-900, 2001 Mar 02.

Article em En | MEDLINE | ID: mdl-29712177

ABSTRACT

ABSTRACT

Comprehensive structure-function analyses are possible with an array comprising more than 800 synthetic variants of a protein domain composed of 44 amino acids. This array was produced by SPOT synthesis on a cellulose membrane and successfully employed for a parallel ligand-binding assay.

Palavras-chave

peptide synthesis; peptides; proteins; solid-phase synthesis

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2001 Tipo de documento: Article

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