Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review.
J Ethnopharmacol
; 224: 149-168, 2018 Oct 05.
Article
em En
| MEDLINE
| ID: mdl-29738847
ABSTRACT
ETHNOPHARMACOLOGICAL USAGES Fructus Alpiniae oxyphyllae (A. oxyphylla) is an important medicinal plant that is used not only as an edible fruit, but also as an important traditional medicine for benefiting cognitive performance and alleviating a wide spectrum of diseases. Such as; warming kidney, securing essence and arresting polyuria, as well as warming the spleen and stopping diarrhea and saliva. AIMS:
The purpose of this review is to provide updated, comprehensive and categorized information on the traditional uses, phytochemistry and pharmacological research of A. oxyphylla in order to explore their therapeutic potential and establish a solid foundation for directing future research. MATERIALS ANDMETHODS:
All the available information on A. oxyphylla was collected via electronic search (using Pubmed, SciFinder, Scirus, Google Scholar and Web of Science) and additionally a number of unpublished resources, (e.g. books, Ph.D. and M.Sc. dissertations, government reports).RESULTS:
Phytochemical research on A. oxyphylla has led to the isolation of components such as essential oils, terpenes, diarylheptanoids, flavones, nucleobases and nucleosides, steroids and others. Crude extracts, fractions and phytochemical constituents isolated from A. oxyphylla showed a wide spectrum of in vitro and in vivo pharmacological activities like neuroprotective, anti-diarrheal, anti-diuretic, anti-neoplastic, anti-oxidant, anti-inflammatory, anti-allergic, viscera protective and anti-diabetic activities. Neuroprotective, anti-cancer, anti-diarrheal and anti-diuretic effects are major areas of research conducted on A. oxyphylla.CONCLUSIONS:
Modern pharmacological studies have supported many traditional uses of A. oxyphylla, including nervous system, urinary system and gastrointestinal system disease. There was convincing evidence in experimental animal models in support of its neuroprotection, secure essence, reduce urination, and anti-carcinogenic effects. However, all the reported pharmacological activities were carried out at pre-clinical level and the authors urge further investigation in clinical trials about these therapeutic fields of A. oxyphylla.Palavras-chave
5-Hydroxymethylfurfural (PubChem CID:237332); Alpinia oxyphylla; Chemical constituents; Chrysin (PubChem CID:5281607); Izalpinin (PubChem CID:5318691); Kaempferide (PubChem CID:5281666); Ligucyperonol (PubChem CID:14681770); Mandassion (PubChem CID:14109869); Nootkatone (PubChem CID:1268142); Oxyphylla A (PubChem CID:637451); Oxyphyllanene D (PubChem CID:57396910); Oxyphyllenone A (PubChem CID:129317404); Oxyphyllenotriol A (PubChem CID:51041015); Oxyphyllol A (PubChem CID:637451); Oxyphyllol B (PubChem CID:11128252); Oxyphyllone G (PubChem CID:51041016); Pharmacological activities; Phytochemistry; Protocatechuic acid (PubChem CID:72); Selin-11-en-4α-ol (PubChem CID:15560330); Sesquiterpenes; Tectochrysin (PubChem CID:5281954); Teuhetenone A (PubChem CID:15153216); Valencene (PubChem CID:9855795); Yakuchinone A (PubChem CID:133145); p-cymene (PubChem CID:7463); ß-nootkatol (PubChem CID:182645)
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alpinia
/
Fitoterapia
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article