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Optimizing charge state distribution is a prerequisite for accurate protein biomarker quantification with LC-MS/MS, as illustrated by hepcidin measurement.
Schmitz, Ellen M H; Leijten, Niels M; van Dongen, Joost L J; Broeren, Maarten A C; Milroy, Lech G; Brunsveld, Luc; Scharnhorst, Volkher; van de Kerkhof, Daan.
Afiliação
  • Schmitz EMH; Expert Center Clinical Chemistry Eindhoven, Eindhoven, The Netherlands.
  • Leijten NM; Catharina Hospital Eindhoven, Clinical Laboratory, Eindhoven, The Netherlands.
  • van Dongen JLJ; Eindhoven University of Technology, Department of Biomedical Engineering, Laboratory of Chemical Biology and Institute for Complex Molecular Systems, Eindhoven, The Netherlands.
  • Broeren MAC; Máxima Medical Center Veldhoven, Clinical Laboratory, Veldhoven, The Netherlands.
  • Milroy LG; Expert Center Clinical Chemistry Eindhoven, Eindhoven, The Netherlands.
  • Brunsveld L; Catharina Hospital Eindhoven, Clinical Laboratory, Eindhoven, The Netherlands.
  • Scharnhorst V; Eindhoven University of Technology, Department of Biomedical Engineering, Laboratory of Chemical Biology and Institute for Complex Molecular Systems, Eindhoven, The Netherlands.
  • van de Kerkhof D; Expert Center Clinical Chemistry Eindhoven, Eindhoven, The Netherlands.
Clin Chem Lab Med ; 56(9): 1490-1497, 2018 08 28.
Article em En | MEDLINE | ID: mdl-29777607
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Hepcidinas Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biomarcadores / Cromatografia Líquida de Alta Pressão / Espectrometria de Massas em Tandem / Hepcidinas Idioma: En Ano de publicação: 2018 Tipo de documento: Article